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Tox & Dermatology - Dr. Kopec

4/13/2017

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Picture
  • Warfarin can cause two dermatologic syndromes: Warfarin Skin Necrosis (thrombotic) and Purple Toe Syndrome (embolic)
  • Cutaneous Anthrax starts as a small, painless papule that transitions to a vesicle then necrotic ulcer with surrounding edema. It is most common on the head, neck, forearms and hands.
  • Blistering Agents are sulfur mustard and lewisite. Sulfur mustard has no pain initially while lewisite there is immediate pain. 
  • Chronic arsenic toxicity is associated with hyperkeratosis, skin pigmentation changes, Blackfoot's disease, lung, bladder and skin cancer. 
  • Mee's line can be seen with arsenic, thallium, heavy metals, renal failure, chemotherapy and sepsis. 
  • Inorganic mercury has been associated with a skin finding called Pink's disease or acrodynia. 
  • Basophillic stipling and Burton's lines can be seen with lead toxicity. 
  • The most common cause is allergic dermatitis is nickel. 
  • Levamisole has been a known contaminant of cocaine causing skin necrosis. 
  • To make the diagnosis of DRESS there must be: rash, fever, and end organ dysfunction.
  • To differentiate between carotenemia vs jaundice, carotenemia can be wiped off with an alcohol wipe and it does not involve the sclera. 
  • Red man syndrome is most commonly seen with vancomycin and rifampin. 

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  • RESIDENCY
    • About CMC
    • Curriculum
    • Benefits
    • Explore Charlotte
    • Official Site
  • FELLOWSHIP
    • EMS
    • Global EM
    • Pediatric EM
    • Toxicology >
      • Tox Faculty
      • Tox Application
    • (All Others)
  • PEOPLE
    • Program Leadership
    • PGY-3
    • PGY-2
    • PGY-1
    • Alumni
  • STUDENTS/APPLICANTS
    • Medical Students at CMC
    • EM Acting Internship
    • Healthcare Disparities Externship
    • Resident Mentorship
  • #FOAMed
    • EM GuideWire
    • CMC Imaging Mastery
    • Pediatric EM Morsels
    • Blogs, etc. >
      • CMC ECG Masters
      • Core Concepts
      • Cardiology Blog
      • Dr. Patel's Coding Blog
      • Global Health Blog
      • Ortho Blog
      • Pediatric Emergency Medicine
      • Tox Blog
  • Chiefs Corner
    • Top 20
    • Current Chiefs
    • Schedules >
      • Conference/Flashpoint
      • Block Schedule
      • ED Shift Schedule
      • AEC Moonlighting
      • Journal Club/OBP/Audits Schedule
      • Simulation
    • Resources >
      • Fox Reference Library
      • FlashPoint
      • Airway Lecture
      • Student Resources
      • PGY - 1
      • PGY - 2
      • PGY - 3
      • Simulation Reading
      • Resident Wellness
      • Resident Research
      • Resume Builder
    • Individualized Interactive Instruction