Core Concepts from Hypertensive Emergencies Trick or Treat? Definitions: Asx HTN <220/120 without complaints HTN urgency >220/120 w/o end organ damage HTN emergency >220/120 + end organ damage When to treat asx HTN? If BP >165/105 + Cr >2, start two agents or >220/>120 without any dysfunction, two agents If 140-165: Controversial, but at the very least, tell the pt and Fast-track them *Social intervention* Rx: No comorbidities: black, all ages: CCB or TZD white, <60 ACEI or ARB white, >60, CCB or TZD HTN + DM: ACEI or ARB + CKD: ACEI or ARB + CAD: BB + ACEI or ARB + CVA: ACEI or ARB + CHF: ACEI or ARB + BB + diuretic HTN Urgency: don't need to treat in the ED. Do at least an EKG and check Cr. Plus fundoscopy and lytes HTN Emergencies- Aortic Dissection Make the Dx and STOP progression Listen for AI murmur and assess for acute heart failure If no murmur and no failure, proceed with IV BB Safe: morphine + nicardipine Hypertensive Encephalopathy Decrease MAP 25% in 8 hours use comorbid appropriate therapy Give something IV and admit ICH Let it ride unless >220/110 generally avoid nitroprusside with neurologic emergencies Pick anything else. We like labetalol Acute Ischemic Stroke If tPA candidate, treat if BP >185/110 Otherwise, protect the penumbra SAH No good guidelines MAP<130 Lookout for complications in the first 24 hours ACS Treat if >160/>110 No lytics if >185/>110 Use NTG (paste, SL, IV), then BB if needed ACHFE the higher the initial BP, the better chance of survival nitro + enalaprilat +/- lasix if they have evidence of fluid overload Cocaine ASA + lorazepam backup: NTG, CCB or phentolamine BB dogma is lifting Eclampsia IV mag + labetalol or hydralazine
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ACEP 2013 Guidelines DO’s 1. Take repeat blood pressures during your patient’s stay in the ED 2. Fast track patients with severely elevated blood pressures (>180/110) to a PCP 3. Start a patient on a maintenance oral antihypertensive if BP severely elevated a. BUT REMEMBER! i. Get a BMP ii.Think about their comorbidities DONT’s 1. HARMFUL! Do NOT give acute antihypertensives (i.e. clonidine, IV drugs) to asymptomatic patients. 2. Send home patient’s WITHOUT any follow up Limitations of ACEP 2013 Guidelines: Do NOT apply these guidelines to patients who have symptoms that may be indicative of a hypertensive emergency, pregnant patients, or patients with end stage renal disease. Cocaine
Treatment of hypertension
Levothyroxine
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