Hemolytic Anemia - Dr. Schwind
Important questions to ask:
S&S - syncope, bleeding, dyspnea, trauma, fatigue, weakness
Workup- What to expect with hemolytic process:
- CBC (Hgb)
- peripheral smear (takes some time, but will often give definitive dx)
- retic count - increased
- haptoglobin - decreased
- LDH - increased
- Coombs (direct and indirect)
- Type and Cross
Intrinsic vs Extrinsic Hemolysis
- Intrinsic = structural or enzymatic defect
- Extrinsic = mechanical or toxic destruction
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