1. All febrile SCD patients get the same initial work-up: H&P, CBC with diff, retic, and BCX
2. ACS = CTX + macrolide (+/- O2 and blood)
3. ACS more likely to develop inpatient... use good pulmonary toilet to prevent
4. Always check the spleen
5. Disposition criteria: home vs. 24H follow-up
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