1. ITP is a diagnosis of exclusion, laboratory findings other than isolated thrombocytopenia and the associated symptoms should suggest an alternative diagnosis.
2. TTP has an extremely high mortality and early initiation of plasma exchange therapy and hematology consult can drastically improve patient outcomes.
3. DIC can be caused by many medical conditions and treatment should be at the underlying cause
4. In general, platelet transfusion is not the appropriate treatment for ITP, TTP and DIC and is often contraindicated